Analysis of drug prevention of venous thromboembolic complications in hip arthroplasty (review)
- Authors: Bochanova E.N.1, Belousov M.A.2, Bozhkova S.A.3, Veselova O.F.1, Golovina N.I.4, Zdzitovetsky D.E.1, Lubnin A.M.1, Shchukin A.A.4
-
Affiliations:
- V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University
- N.S. Karpovich Krasnoyarsk Interdistrict Clinical Emergency Hospital
- Vreden Russian Research Institute of Traumatology and Orthopedics
- Krasnoyarsk Territory Clinical Hospital
- Issue: Vol 21, No 3 (2015)
- Pages: 70-75
- Section: Experience exchange
- Submitted: 12.09.2016
- Published: 12.10.2015
- URL: https://journal.rniito.org/jour/article/view/147
- DOI: https://doi.org/10.21823/2311-2905-147
- ID: 147
Cite item
Full Text
Abstract
The retrospective analysis of 131 medical records of patients who underwent surgery for total hip arthroplasty in two large hospitals in Krasnoyarsk in 2013 was made. All patients received anticoagulants for the purpose of thromboprophylaxis. In the structure of these drugs prevails prescriptions anticoagulant with a low risk of bleeding, requiring no laboratory control, such as low molecular weight heparins and direct oral anticoagulants. The assessment of anticoagulant dosing regimens revealed defects related to non-compliance as a single dose and duration of use after discharge from hospital. To eliminate the detected defects is necessary to conduct training seminars, the approval of the local protocol of prevention and formation of the VTEC system audit.
About the authors
E. N. Bochanova
V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University
Author for correspondence.
Email: bochanova@list.ru
Россия
M. A. Belousov
N.S. Karpovich Krasnoyarsk Interdistrict Clinical Emergency Hospital
Email: noemail@neicon.ru
Россия
S. A. Bozhkova
Vreden Russian Research Institute of Traumatology and Orthopedics
Email: noemail@neicon.ru
Россия
O. F. Veselova
V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University
Email: noemail@neicon.ru
Россия
N. I. Golovina
Krasnoyarsk Territory Clinical Hospital
Email: noemail@neicon.ru
Россия
D. E. Zdzitovetsky
V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University
Email: noemail@neicon.ru
Россия
A. M. Lubnin
V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University
Email: noemail@neicon.ru
Россия
A. A. Shchukin
Krasnoyarsk Territory Clinical Hospital
Email: noemail@neicon.ru
Россия
References
- Божкова С.А., Тихилов Р.М., Борисов А.М., Цыбин А.В. Опыт организации тромбопрофилактики в стационаре травматологоортопедического профиля. Флебология. 2012; (4):49-54.
- Божкова С.А., Новокшонова А.А., Дроздова П.В. Аспекты практического применения прямых оральных антикоагулянтов в стационаре травматологоортопедического профиля. Хирургия. 2014; (11):48-54.
- Гарифуллов Г.Г., Коваленко А.Н. Антикоагулянтная профилактика тромбоэмболических осложнений при эндоротезировании тазобедренного сустава. Практическая медицина. 2010; (8):89-92.
- Российские клинические рекомендации по диагностике, профилактике и лечению венозных тромбоэмболических осложнений. Флебология. 2010; (2-1):2-37.
- Российские клинические рекомендации по профилактике венозных тромбоэмболических осложнений в травматологии и ортопедии. Травматология и ортопедия России. 2012; (1):1-24.
- Douketis J.D., Eikelboom J.W., Quinlan D.J., Willan A.R., Crowther M.A. Short-duration prophylaxis against venous thromboembolism after total hip or knee replacement: a meta-analysis of prospective studies investigating symptomatic outcomes. Arch Intern Med. 2002; 162(13):1465-1471.
- Geerts W.H., Pineo G.F., Heit J.A., Bergqvist D., Lassen M.R., Colwell C.W., Ray J.G. Prevention of venous thromboembolism: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest. 2004; 126(3 Suppl):338S-400S.
- Samama C.M., Ravaud P., Parent F., Barré J., Mertl P., Mismetti P. Epidemiology of venous thromboembolism after lower limb arthroplasty: the FOTO study. J Thromb Haemost. 2007; 5(12):2360-2367.
- Warwick D., Friedman R.J., Agnelli G., GilGaray E., Johnson K., FitzGerald G., Turibio F.M. Insufficient duration of venous thromboembolism prophylaxis after total hip or knee replacement when compared with the time course of thromboembolic events: findings from the Global Orthopaedic Registry. J Bone Joint Surg Br. 2007; 89(6):799-807.
- White R.H., Zhou H., Romano P.S. Incidence of symptomatic venous thromboembolism after different elective or urgent surgical procedures. Thromb Haemost. 2003; 90(3):446-455.