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Assessment the Accuracy of Densitometry Measurements Using DMA PP2 Phantom
- Authors: Petraikin A.V.1, Smoliarchuk M.Y.1, Petryaykin F.A.2, Nisovtsova L.A.1, Artyukova Z.R.3, Sergunova K.A.1, Akhmad E.S.1, Semenov D.S.1, Vladzymyrsky A.V.1, Morozov S.P.1
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Affiliations:
- Practical and Clinical Research Center of Diagnostics and Telemedicine Technologies
- Lomonosov Moscow State University
- Sechenov First Moscow State Medical University (Sechenov University)
- Issue: Vol 25, No 3 (2019)
- Pages: 124-134
- Section: METHODS OF EXAMINATIONS
- Submitted: 17.10.2019
- Accepted: 17.10.2019
- Published: 17.10.2019
- URL: https://journal.rniito.org/jour/article/view/1305
- DOI: https://doi.org/10.21823/2311-2905-2019-25-3-124-134
- ID: 1305
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Abstract
Purpose of the study — to assess the accuracy of dual energy x-ray absorptiometry (DXA ) for measurements of mineral bone density, bone mineral content, area of selected spine zone of examination as well as impact of subcutaneous fat layer and correction of auto-segmenting of the spine on the mentioned parameters. Material and Methods. The study was performed on iDXA scanner using the designed phantom DMA PP2 of the lumber spine with inlays to simulate subcutaneous fat (SF). To ensure correct assessment of measurements (precision and accuracy) the authors performed fivefold repeated scanning. Two modifications of the phantom were used, with and without SF inlays, as well as two methods for selection of spine range for examination – automatic and correction of autosegmentation. Results. Scanning of the phantom without SF inlays demonstrated a systematic understated values of bone mineral density (BMD) and bone mineral content (BMC) along the full measured interval: mean relative error of BMD for L1-L4 interval was 10.62% with automatic segmentation and 7.43% — with correction of autosegmentation. The least accuracy for BMD and BMC (1.53% and 0.90%, respectively) was observed during SF simulation and with correction of auto-segmentation of the spine. Analysis of variation coefficient for area of examined vertebrae, BMC and BMD demonstrated rather high precision of measurements, namely for BMD without SF in the L1-L4 interval amounted to 1.00% (auto-segmentation) and 0.56% (correction). Variation coefficient for scanning including SF inlays in the interval L1-L4 was 1.00% (auto-segmentation) and 0.68% (correction). Conclusion. The lowest level of accuracy was observed with the SFL object; in this case, the variation coefficient did not exceed 1% for all BMD interval. The mean value of the BMC accuracy also did not exceed 1% with the optimal scan parameters. The study proved the effectiveness of “RSK PK2” phantom when estimating the accuracy of BMD and BMC on iDXA scanner.
About the authors
A. V. Petraikin
Practical and Clinical Research Center of Diagnostics and Telemedicine Technologies
Author for correspondence.
Email: alexeypetraikin@gmail.com
Cand. Sci. (Med.), Senior Researcher, Technical Monitoring and QA Development
Moscow
РоссияM. Ya. Smoliarchuk
Practical and Clinical Research Center of Diagnostics and Telemedicine Technologies
Email: fake@neicon.ru
Research Officer, Nuclear Medicine Physician
Moscow
РоссияF. A. Petryaykin
Lomonosov Moscow State University
Email: fake@neicon.ru
Resident, Department of Fundamental Medicine
Moscow
РоссияL. A. Nisovtsova
Practical and Clinical Research Center of Diagnostics and Telemedicine Technologies
Email: fake@neicon.ru
Dr. Sci. (Med.), Professor, Chief Researcher
Moscow
РоссияZ. R. Artyukova
Sechenov First Moscow State Medical University (Sechenov University)
Email: fake@neicon.ru
Student
Moscow
РоссияK. A. Sergunova
Practical and Clinical Research Center of Diagnostics and Telemedicine Technologies
Email: fake@neicon.ru
Cand. Sci. (Tech.), Head of Technical Monitoring and QA Development Department
Moscow
РоссияE. S. Akhmad
Practical and Clinical Research Center of Diagnostics and Telemedicine Technologies
Email: fake@neicon.ru
Researcher, Technical Monitoring and QA Development
Moscow
РоссияD. S. Semenov
Practical and Clinical Research Center of Diagnostics and Telemedicine Technologies
Email: fake@neicon.ru
Researcher, Technical Monitoring and QA Development Department
Moscow
РоссияA. V. Vladzymyrsky
Practical and Clinical Research Center of Diagnostics and Telemedicine Technologies
Email: fake@neicon.ru
Dr. Sci. (Med.), Deputy Director for Science
Moscow
РоссияS. P. Morozov
Practical and Clinical Research Center of Diagnostics and Telemedicine Technologies
Email: fake@neicon.ru
Dr. Sci. (Med.), Professor, Director
Moscow
РоссияReferences
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