Management of Chronic Pain Syndrome in Knee Osteoarthritis with Selective Embolization of Popliteal Artery Branches: Review

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Abstract

Background. Treatment of knee osteoarthritis (OA) in early stages as well as the pain syndrome associated with it usually suggests the combination of medicines and physical therapy means. However, no method has proven its absolute efficiency yet. Transcatheter arterial embolization of popliteal branches is a new minimally invasive treatment that is currently being studied and tested. The objective of our research was the analysis as well as generalization of the outcomes of the pain syndrome in knee OA treatment with the selective embolization of popliteal branches. Materials and Methods. The reviewed articles were retrieved from PubMed database and eLIBRARY digital library considering the criteria like the emboli material, size, and type; possible complications and their effect on the outcome; the patient enrolment criteria for this type of surgical management; the short and long-term outcomes. Results. Transcatheter arterial embolization of popliteal branches is a new minimally invasive method of knee OA treatment. All authors revealed the pathology growth of the vasculature and its complete embolization as a result of the intervention. The review articles present a significant abatement in patients resistant to conventional medical treatment, minimal possible complications, and good long-term outcomes. Conclusion. Since this method of knee OA management is new and understudied, and the number of the published findings does not exceed two hundred it required further thorough investigation and randomized clinical trials.

About the authors

M. N. Kozadaev

V.I. Razumovsky Saratov State Medical University, Scientific Research Institute of Traumatology, Orthopedics and Neurosurgery

Author for correspondence.
Email: m_kozadaev_ortoped@mail.ru
ORCID iD: 0000-0001-6235-7193

Maksim N. Kozadaev — Cand. Sci. (Med.), Researcher, Department of Fundamental, Clinical and Experimental Research

Saratov

Russian Federation

I. N. Shchanitsyn

V.I. Razumovsky Saratov State Medical University, Scientific Research Institute of Traumatology, Orthopedics and Neurosurgery

Email: dr.green@list.ru
ORCID iD: 0000-0003-0565-5172

Ivan N. Shchanitsyn — Cand. Sci. (Med.), Senior Researcher, Department of Innovative Projects for Neurosurgery and Vertebrology

Saratov

Russian Federation

M. V. Girkalo

V.I. Razumovsky Saratov State Medical University, Scientific Research Institute of Traumatology, Orthopedics and Neurosurgery

Email: girkalo@mail.ru
ORCID iD: 0000-0001-5847-1153

Mikhail V. Girkalo — Cand. Sci. (Med.), Deputy Director

Saratov

Russian Federation

S. P. Bazhanov

V.I. Razumovsky Saratov State Medical University, Scientific Research Institute of Traumatology, Orthopedics and Neurosurgery

Email: baj.s@mail.ru
ORCID iD: 0000-0001-9474-9095

Sergey P. Bazhanov — Cand. Sci. (Med.), Leading Researcher, Department of Innovative Projects for Neurosurgery and Vertebrology

Saratov

Russian Federation

V. Yu. Ulyanov

V.I. Razumovsky Saratov State Medical University, Scientific Research Institute of Traumatology, Orthopedics and Neurosurgery

Email: v.u.ulyanov@gmail.com
ORCID iD: 0000-0002-9466-8348

Vladimir Yu. Ulyanov — Dr. Sci. (Med.), Deputy Director

Saratov

Russian Federation

O. A. Kauts

V.I. Razumovsky Saratov State Medical University, Scientific Research Institute of Traumatology, Orthopedics and Neurosurgery

Email: oandreevich2009@yandex.ru
ORCID iD: 0000-0003-1822-1939

Oleg A. Kauts — Cand. Sci. (Med.), Senior Researcher, Department of Innovative Projects for Traumatology and Orthopedics

Saratov

Russian Federation

References

  1. Матвеев Р.П., Брагина С.В. Остеоартроз коленного сустава: проблемы и социальная значимость. Экология человека. 2012;(9):53-62.
  2. Scott C.E.H., MacDonald D.J., Howie C.R. ‘Worse than death’ and waiting for a joint arthroplasty. Bone Joint J. 2019;101-B:941-950. doi: 10.1302/0301-620X.101B8.
  3. Bayliss L.E., Culliford D., Monk A.P., Glyn-Jones S., Prieto-Alhambra D., Judge A. et al. The effect of patient age at intervention on risk of implant revision after total replacement of the hip or knee: a populationbased cohort study. Lancet. 2017;389(10077):1424-1430. doi: 10.1016/S0140-6736(17)30059-4.
  4. Losina E., Katz J.N. Total knee arthroplasty on the rise in younger patients: Are we sure that past performance will guarantee future success? Arthritis Rheum. 2012;64(2):339-341. doi: 10.1002/art.33371.
  5. Collins J.E., Deshpande B.R., Katz J.N., Losina E. Race- and sex-specific incidence rates and predictors of total knee arthroplasty: seven-year data from the osteoarthritis initiative. Arthritis Care Res. 2016;68(7):965-973. doi: 10.1002/acr.22771.
  6. Bagla S., Piechowiak R., Hartman T., Orlando J., Del Gaizo D., Isaacson A. Genicular artery embolization for the treatment of knee pain secondary to osteoarthritis. J Vasc Interv Radiol. 2019;31(7):1-7. doi: 10.1016/j.jvir.2019.09.018.
  7. Lee S.H., Hwang J.H., Kim D.H., So Y.H., Park J., Cho S.B. et al. Clinical outcomes of transcatheter arterial embolisation for chronic knee pain: mildto-moderate versus severe knee osteoarthritis. Cardiovasc Intervent Radiol. 2019;42(11):1530-1536. doi: 10.1007/s00270-019-02289-4.
  8. Okuno Y., Korchi A.M., Shinjo T., Kato S. Transcatheter arterial embolization as a treatment for medial knee pain in patients with mild to moderate osteoarthritis. Cardiovasc Intervent Radiol. 2015;38(2):336-343. doi: 10.1007/s00270-014-0944-8.
  9. Okuno Y., Korchi A.M., Shinjo T., Kato S., Kaneko T. Midterm clinical outcomes and MR imaging changes after transcatheter arterial embolization as a treatment for mild to moderate radiographic knee osteoarthritis resistant to conservative treatment. J Vasc Interv Radiol. 2017;28(7):995-1002. doi: 10.1016/j.jvir.2017.02.033.
  10. Iwamoto W., Okuno Y., Matsumura N., Kaneko T., Ikegami H. Transcatheter arterial embolization of abnormal vessels as a treatment for lateral epicondylitis refractory to conservative treatment: a pilot study with a 2-year follow-up. J Shoulder Elb Surg. 2017;26(8):13351341. doi: 10.1016/j.jse.2017.03.026.
  11. Ogilvie E., Tutton S.M., Neilson J.C., Rilling W.S., Hohenwalter E.J. Geniculate artery embolization for management of recurrent hemarthrosis: A single-center experience. J Vasc Interv Radiol. 2016;27(7):1097-1099. doi: 10.1016/j.jvir.2016.04.003.
  12. Guevara C.J., Lee K.A., Barrack R., Darcy M.D. Technically successful geniculate artery embolization does not equate clinical success for treatment of recurrent knee hemarthrosis after knee surgery. J Vasc Interv Radiol. 2016;27(3):383-387. doi: 10.1016/j.jvir.2015.11.056.
  13. Lauko K., Tangchaiburana S., Padia S.A. Transarterial genicular artery embolization as treatment of painful knee osteoarthritis in a 64-year-old woman. J Radiol Nurs. 2020;39(2):89-91. doi: 10.1016/j.jradnu.2020.02.002.
  14. Korchi A.M., Cengarle-Samak A., Okuno Y., MartelPelletier J., Pelletier J.P., Boesen M. et al. inflammation and hypervascularization in a large animal model of knee osteoarthritis: imaging with pathohistologic correlation. J Vasc Interv Radiol. 2019;30(7):1116-1127. doi: 10.1016/j.jvir.2018.09.031.
  15. Kardos D., Marschall B., Simon M., Hornyák I., Hinsenkamp A., Kuten O. et al. Investigation of cytokine changes in osteoarthritic knee joint tissues in response to hyperacute serum treatment. Cells. 2019;8(8):824. doi: 10.3390/cells8080824.
  16. Sellam J., Berenbaum F. The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis. Nat Rev Rheumatol. 2010;6(11):625-635. doi: 10.1038/nrrheum.2010.159.
  17. Антипов В.А., Смышляев И.А., Тумаков М.И., Гильфанов С.И. Возможности суперселективной эмболизации ветвей подколенной артерии при лечении остеоартроза коленного сустава на ранних стадиях Обзор современной литературы, анализ мирового опыта. Кремлевская медицина. Клинический вестник. 2019;(2):100-117. doi: 10.26269/y4wv-cn09
  18. Mapp P.I., Walsh D.A. Mechanisms and targets of angiogenesis and nerve growth in osteoarthritis. Nat Rev Rheumatol. 2012;8(7):390-398. doi: 10.1038/nrrheum.2012.80.
  19. Delbarre A., Amor B., Bardoulat I., Tetafort A., Pelletier-Fleury N. Do intra-articular hyaluronic acid injections delay total knee replacement in patients with osteoarthritis – A Cox model analysis. PLoS One. 2017;12(11):e0187227. doi: 10.1371/journal.pone.0187227.
  20. Чесников С.Г., Розенберг Д.В., Тимошенко М.Е., Дедяев С.И. Опыт применения методики PRPтерапии в лечении пациентов с гонартрозом. Клиническая практика. 2018;9(3):22-24. doi: 10.17816/clinpract09322-24.
  21. Adriani E., Moio M., Paola Di B., Salustri W., Alfieri A., Parisi P. et al. Percutaneous fat transfer to treat knee osteoarthritis symptoms: preliminary results. Joints. 2017;5(2):89-92. doi: 10.1055/s-0037-1603672.
  22. Rahimzadeh P., Imani F., Faiz S.H.R., Alebouyeh M.R., Azad-Ehyaei D., Bahari L. et al. Adding intraarticular growth hormone to platelet rich plasma under ultrasound guidance in knee osteoarthritis: A comparative double-blind clinical trial. Anesthesiol Pain Med. 2016;6(6):e41719. doi: 10.5812/aapm.41719.
  23. Raynauld J.P., Buckland-Wright C., Ward R., Choquette D., Haraoui B., Martel-Pelletier J. et al. Safety and efficacy of long-term intraarticular steroid injections in osteoarthritis of the knee: A randomized, double-blind, placebo-controlled trial. Arthritis Rheum. 2003;48(2):370-377. doi: 10.1002/art.10777.
  24. Nguyen C., Rannou F. The safety of intra-articular injections for the treatment of knee osteoarthritis: a critical narrative review. Expert Opin Drug Saf. 2017;16(8):897-902. doi: 10.1080/14740338.2017.1344211.
  25. Hunter D.J. Viscosupplementation for osteoarthritis of the knee. N Engl J Med. 2015;372(11):1040-1047. doi: 10.1056/NEJMc1505801.
  26. Kabiri A., Hashemibeni B., Pourazar A., Mardani M., Esfandiari E., Esmaeili A. Platelet-rich plasma application in chondrogenesis. Adv Biomed Res. 2014;3(1):138. doi: 10.4103/2277-9175.135156.
  27. Huang P.H., Wang C.J., Chou W.Y., Wang J.W., Ko J.Y. Short-term clinical results of intra-articular PRP injections for early osteoarthritis of the knee. Int J Surg. 2017;42:117-122. doi: 10.1016/j.ijsu.2017.04.067.
  28. Sampson S., Gerhardt M., Mandelbaum B. Platelet rich plasma injection grafts for musculoskeletal injuries: a review. Curr Rev Musculoskelet Med. 2008;1(3-4):165-174. doi: 10.1007/s12178-008-9032-5.
  29. Cook C.S., Smith P.A. Clinical update: why PRP should be your first choice for injection therapy in treating osteoarthritis of the knee. Curr Rev Musculoskelet Med. 2018;11(4):583-592. doi: 10.1007/s12178-018-9524-x.
  30. Chahla J., Piuzzi N.S., Mitchell J.J., Dean C.S., PascualGarrido C., LaPrade R.F. et al. Intra-articular cellular therapy for osteoarthritis and focal cartilage defects of the knee: A systematic review of the literature and study quality analysis. J Bone Joint Surg Am. 2016;98(18):15111521. doi: 10.2106/JBJS.15.01495.
  31. LaPrade R.F., Dragoo J.L., Koh J.L., Murray I.R., Geeslin A.G., Chu C.R. AAOS research symposium updates and consensus: Biologic treatment of orthopaedic injuries. J Am Acad Orthop Surg. 2016;24(7):e62-78. doi: 10.5435/JAAOS-D-16-00086.
  32. Shaw B., Darrow M., Derian A. Short-term outcomes in treatment of knee osteoarthritis with 4 bone marrow concentrate injections. Clin Med Insights Arthritis Musculoskelet Disord. 2018;11:1179544118781080. doi: 10.1177/1179544118781080.
  33. Shapiro S.A., Kazmerchak S.E., Heckman M.G., Zubair A.C., O’Connor M.I. A prospective, single-blind, placebo-controlled trial of bone marrow aspirate concentrate for knee osteoarthritis. Am J Sports Med. 2017;45(1):82-90. doi: 10.1177/0363546516662455.
  34. Filippiadis D., Charalampopoulos G., Mazioti A., Alexopoulou E., Vrachliotis T., Brountzos E. et al. Interventional radiology techniques for pain reduction and mobility improvement in patients with knee osteoarthritis. Diagn Interv Imaging. 2019;100(7-8):391-400. doi: 10.1016/j.diii.2019.02.011.
  35. Iijima H., Isho T., Kuroki H., Takahashi M., Aoyama T. Effectiveness of mesenchymal stem cells for treating patients with knee osteoarthritis: a meta-analysis toward the establishment of effective regenerative rehabilitation. NPJ Regen Med. 2018;3(1):15. doi: 10.1038/s41536-018-0041-8.
  36. Goldman D.T., Piechowiak R., Nissman D., Bagla S., Isaacson A. Current concepts and future directions of minimally invasive treatment for knee pain. Curr Rheumatol Rep. 2018; 20(9):54. doi: 10.1007/s11926-018-0765-x.
  37. Iannaccone F., Dixon S., Kaufman A. A review of longterm pain relief after genicular nerve radiofrequency ablation in chronic knee osteoarthritis. Pain Physician. 2017;20(3):E437-44.
  38. Ariel de Lima D., Gonçalves M.C.K., Grando S.T.C.E.S., Cintra T.L.L., Pinto D.M., Gonçalves R.K. Indications of the neurotomy of genicular nerves by radiofrequency for the treatment of knee osteoarthritis: A literature review. Rev Bras Ortop. 2019;54(3):233-240. doi: 10.1055/s-0039-1692121.
  39. Woodhams R., Nishimaki H., Ogasawara G., Fujii K., Yamane T., Ishida K. et al. Imipenem/cilastatin sodium (IPM/CS) as an embolic agent for transcatheter arterial embolisation: A preliminary clinical study of gastrointestinal bleeding from neoplasms. Springerplus. 2013;2(1):344. doi: 10.1186/2193-1801-2-344.
  40. Kolber M.K., Shukla P.A., Kumar A., Zybulewski A., Markowitz T., Silberzweig J.E. Endovascular management of recurrent spontaneous hemarthrosis after arthroplasty. Cardiovasc Intervent Radiol. 2017;40(2):216-222. doi: 10.1007/s00270-016-1511-2.
  41. Bagla S., Rholl K.S., van Breda A., Sterling K.M., van Breda A. Geniculate artery embolization in the management of spontaneous recurrent hemarthrosis of the knee: case series. J Vasc Interv Radiol. 2013;24(3):439-442. doi: 10.1016/j.jvir.2012.11.011.
  42. Lombardi M., Cardenas A.C. Hemarthrosis. In: Treasure Island (FL): StatPearls Publishing; 2020. Available from: https://www.ncbi.nlm.nih.gov/books/NBK525999.
  43. Choi Y-J., Ra H.J. Patient satisfaction after total knee arthroplasty. Knee Surg Relat Res. 2016;28(1):1-15. doi: 10.5792/ksrr.2016.28.1.1.
  44. Kahlenberg C.A, Nwachukwu B.U., McLawhorn A.S., Cross M.B., Cornell C.N., Padgett D.E. Patient satisfaction after total knee replacement: a systematic review. HSS J. 2018;14(2):192-201. doi: 10.1007/s11420-018-9614-8.
  45. Robertsson O., Sundberg M., Lidgren L., W-Dhal A. Annual report 2016 – The Swedish Knee Arthroplasty Register. Available from: https://www.researchgate.net/publication/311439835_Annual_report_2016_-_The_Swedish_Knee_Arthroplasty_Register.
  46. Chau Y., Roux C., Breuil V., Trojani C., Gonzalez J.F., Amoretti N. et al. Endovascular occlusion of neovascularization as a treatment for persistent pain after total knee arthroplasty. Cardiovasc Intervent Radiol. 2020;43(5):787-790. doi: 10.1007/s00270-020-02449-x.
  47. Okuno Y., Oguro S., Iwamoto W., Miyamoto T., Ikegami H., Matsumura N. Short-term results of transcatheter arterial embolization for abnormal neovessels in patients with adhesive capsulitis: A pilot study. J Shoulder Elb Surg. 2014;23(9):e199-206. doi: 10.1016/j.jse.2013.12.014.
  48. Hwang J.H., Park S.W., Kim K.H., Lee S.J., Oh K.S., Chung S.W. et al. Early results of transcatheter arterial embolization for relief of chronic shoulder or elbow pain associated with tendinopathy refractory to conservative treatment. J Vasc Interv Radiol. 2018;29(4):510-517. doi: 10.1016/j.jvir.2017.11.013.

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