Email this article 
Retracted: Comparison Outcomes of Discover Total Disk Arthroplasty and Anterior Cervical Discectomy with Fusion in Surgical Treatment of Cervical Disk Degenerative Disease: a Meta-Analysis of Randomized Trials
- Authors: Byvaltsev V.A.1,2,3, Stepanov I.A.1, Aliyev M.A.1, Avakov BM.1, Yussupov B.R.1, Shepelev V.V.1
-
Affiliations:
- ФГБОУ ВО «Иркутский государственный медицинский университет»
- НУЗ «Дорожная клиническая больница на ст. Иркутск-Пассажирский»
- ФГБНУ «Иркутский научный центр хирургии и травматологии»4 ФГБОУ ДПО «Иркутская государственная медицинская академия последипломного образования»
- Issue: Vol 24, No 4 (2018)
- Pages: 137-147
- Section: Reviews
- Submitted: 29.12.2018
- Accepted: 29.12.2018
- Published: 29.12.2018
- URL: https://journal.rniito.org/jour/article/view/1107
- DOI: https://doi.org/10.21823/2311-2905-2018-24-4-137-147
- ID: 1107
Cite item
Abstract
The purpose — to compare the effectiveness of Discover cervical disk arthroplasty (CDA) and anterior cervical discectomy with fusion (ACDF) in the surgical treatment of cervical intervertebral disk (IVD) degenerative disease.
Study design — a meta-analysis of randomized clinical trials.
Material and Methods. Randomized clinical trials were conducted in the Pubmed, EMBASE, ELibrary and Cochrane Library databases published from 2008 to October 2018, which compared the results of Discover CDA and ACDF techniques in the surgical treatment of cervical IVD degenerative disease. For dichotomous variables, the relative risk and 95% confidence interval were calculated, standardized difference of mean values and their 95% confidence interval were used for continuous variables using the random effects model.
Results. This meta-analysis included 9 randomized controlled clinical trials, including the results of surgical treatment of 513 patients with degenerative disease of the cervical IVD. In the CDA group, the operation time was significantly shorter, in contrast to the group of patients who underwent ACDF (p<0.0001). The values of blood loss (p = 0.89), levels of quality of life for patients according to the Neck Disability Index (NDI) (p = 0.22), severity of pain in the cervical spine (p = 0.50) and upper limbs on a visual analogue scale (VAS) (p = 0.16), as well as the prevalence of secondary surgical procedures (p = 0.68) and adverse events (p = 0.40) between the compared groups did not have significant differences. At the same time, significantly large values of the range of motion at the operated level were noted in the CDA group (p<0.00001).
Conclusion. Discover CDA in comparison with ACDF has a significantly large values of range of motion at the operated level. At the same time, there were no statistically significant differences in the NDI scores, VAS pain scores in cervical spine and upper limbs, and the prevalence of secondary surgical procedures and adverse events between the compared groups of respondents were not identified.
About the authors
V. A. Byvaltsev
ФГБОУ ВО «Иркутский государственный медицинский университет»;НУЗ «Дорожная клиническая больница на ст. Иркутск-Пассажирский»;
ФГБНУ «Иркутский научный центр хирургии и травматологии»4
ФГБОУ ДПО «Иркутская государственная медицинская академия последипломного образования»
Author for correspondence.
Email: vadimabyvaltsev@gmail.com
Vadim A. Byvaltsev — Dr. Sci. (Med.), head of Neurosurgery and Innovative Medicine Department at Irkutsk State Medical University; chief of Neurosurgery in the JSC «Russian Railways»; head of Neurosurgical Center at Road Clinical Hospital at «Irkutsk-Passazhirskiy» Station; vice-president of Irkutsk Scientific Center of Surgery and Traumatology; professor of the Department of Traumatology, Orthopaedics and Neurosurgery, Irkutsk State Medical Academy of Continuing Education
Irkutsk
РоссияI. A. Stepanov
ФГБОУ ВО «Иркутский государственный медицинский университет»
Email: fake@neicon.ru
Ivan A. Stepanov — postgraduate student
Irkutsk
РоссияM. A. Aliyev
ФГБОУ ВО «Иркутский государственный медицинский университет»
Email: fake@neicon.ru
Marat A. Aliyev — doctoral student
Irkutsk
РоссияB M. Avakov
ФГБОУ ВО «Иркутский государственный медицинский университет»
Email: fake@neicon.ru
Bakhyt M. Avakov — postgraduate student
Irkutsk
РоссияB. R. Yussupov
ФГБОУ ВО «Иркутский государственный медицинский университет»
Email: fake@neicon.ru
Bobur R. Yussupov — postgraduate student
Irkutsk
РоссияV. V. Shepelev
ФГБОУ ВО «Иркутский государственный медицинский университет»
Email: fake@neicon.ru
Valerii V. Shepelev — doctoral student
Irkutsk
Россия
References
- Бывальцев В.А., Сороковиков В.А., Калишш А.А., Белых Е.Г. Анализ результатов переднего шейного спондилодеза с использованием гибридного кейджа РСВ Evolution за двухлетний период. Вопросы нейрохирургии им. Н.Н. Бурденко. 2013;77(1):37-54.
- Klingjer J.-H., Kruger M.T., Sircar R., Kogias E., Scholz C., Volz F. et al. PEEK cages versus PMMA spacers in anterior cervical discectomy: comparison of fusion, subsidence, sagittal alignment, and clinical outcome with a minimum 1-year follow-up. ScientificWorldfoumaL 2014;2014:398396. doi: 10.1155/2014/398396.
- Guan L., Hai Y., Yang J. C., Zhou L.-J., Chen X.- L. Anterior cervical discectomy and fusion may be more effective than anterior cervical corpectomy and fusion for the treatment of cervical spondylotic myelopathy. BMC Musculoskelet Disord 2015;16:29. doi: 10.1186/S12891-015-0490-9.
- Oh C.H., Kim D.Y., Ji G.Y., Kim Y.J., Yoon S.H., Hyun D. et al. Cervical arthroplasty for moderate to severe disc degeneration: clinical and radiological assessments after a minimum follow-up of 18 months: pfirrmarm grade and cervical arthroplasty. YonseiMedJ. 2014;55(4):1072- 1079. doi: 10.3349/ymj.2014.55.4.1072.
- Бывальцев B.A., Калинин A.A., Степанов И.А., Пестряков Ю.Я., Шепелев В.В. Анализ результатов применения тотальной артропластики межпозвонкового диска шейного отдела позвоночника протезом М6-С: мультицентровое исследование. Вопросы нейрохирургии им. Н.Н. Бурденко. 2017;81(5):46-55. doi: 10.17116/neuro201781546-55.
- Maharaj M.M., Mobbs R.J., Hogan J., Zhao D.F., Rao P.J., Phan K. Anterior cervical disc arthroplasty (ACDA) versus anterior cervical discectomy and fusion (ACDF): a systematic review and meta-analysis. J Spine Surg. 2015;l(l):72-85. doi: 10.3978/j.issn.2414-469X.2015.09.01.
- Chen Y., Wang X., Lu X., Yang H., Chen D. Cervical disk arthroplasty versus ACDF for preoperative reducible kyphosis. Orthopedics. 2013;36(7):958-965. doi: 10.3928/01477447-20130624-29.
- Luo C., Ou X., Chen B., Peng Z.Y., Zou Y.G. Cervical disc arthroplasty versus cervical discectomy and fusion for single-level cervical spondylosis: midterm follow-up of a randomized controlled trial. Chin J Tissue Engin Res. 2015;19(9):1358-1364. 10.3969/j.issn.2095-4344.2015.09.008.
- Rozankovic M., Marasanov S.M., Vukic M. Cervical disc replacement with discover versus fusion in a single level cervical disc disease: a prospective single center randomized trial with a minimum two-year foUow-up. Clin Spine Surg. 2017;30(5):E515-E522. doi: 10.1097/BSD.0000000000000170.
- Shi S., Zheng S., Li X.F., Yang L.L., Liu Z.D., Yuan W. Comparison of 2 zero-profile implants in the treatment of single-level cervical spondylotic myelopathy: a prehminary clinical study of cervical disc arthroplasty versus fusion. PLoS One. 2016;ll(7):e0159761. doi: 10.1371/joumal.pone.0159761.
- Skepphohn M., Lindgren L., Henriques T., Vavruch L., Lofgren H., Olerud C. The Discover artificial disc replacement versus fusion in cervical radiculopathy — a randomized controlled outcome trial with 2-year follow-up. Spine J. 2015;15(6):1284-1294. D01:10.1016/j.spinee.2015.02.039.
- Sun O., Lei S., Peijia L., Hanping Z., Hongwei H., Junsheng C., Jianmin L. A comparison of zero- profile devices and artificial cervical disks in patients with 2 noncontiguous levels of cervical spondylosis. Clinical spine surgery. 2016;29(2):E61-66. doi: 10.1097/BSD.0000000000000096.
- Liberati A., Altman D.G., Tetzlaff J., Muhow C., Gotzsche P.C., loannidis J.P. et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. / Clin Epidemiol. 2009;62(10):el-34. doi: 10.1016/j.jclinepi.2009.06.006.
- Jadad A.R., Moore R.A., Carroll D., Jenkinson C., Reynolds D.J., Gavagjian D.J., McOuay H.J. Assessing the quahty of reports of randomized clinical trials: is bhndingnecessary? Control Clin Trials. 1996;17(1):1-12.
- Xie L., Liu M., Ding F., Li R, Ma D. Cervical disc arthroplasty (CDA) versus anterior cervical discectomy and fusion (ACDF) in symptomatic cervical degenerative disc diseases (CDDDs): an updated meta-analysis of prospective randomized controlled trials (RCTs). SpringerPlus. 2016;5(1):1188. doi: 10.1186/S40064-016-2851-8.
- Zou S., Gao J., Xu B., Lu X., Han Y., Meng H. Anterior cervical discectomy and fusion (ACDF) versus cervical disc arthroplasty (CDA) for two contiguous levels cervical disc degenerative disease: a meta-analysis of randomized controlled trials. Eur Spine /. 2017;26(4):985-997. doi: 10.1007/S00586-016-4655-5.
- Hu Y., Lv G., Ren S., Johansen D. Mid- to long-term outcomes of cervical disc arthroplasty versus anterior cervical discectomy and fusion for treatment of symptomatic cervical disc disease: a systematic review and meta-analysis of eight prospective randomized controlled trials. PLoS One. 2016;ll(2):e0149312. doi: 10.1371/joumal.pone.0149312.
- Wu A.-M., Xu H., Mullinix K.P., Jin H.M., Huang Z.Y., Lv Q.B. et al. Minimum 4-year outcomes of cervical total disc arthroplasty versus fusion: a metaanalysis based on prospective randomized controlled trials. Medicine (Baltimore). 2015;94(15):e665. doi: 10.1097/MD.0000000000000665.
- Rao M.J., Nie S.P., Xiao B.W., Zhang G.H., Gan X.R., Cao S.S. Cervical disc arthroplasty versus anterior cervical discectomy and fusion for treatment of symptomatic cervical disc disease: a meta-analysis of randomized controlled trials. Arch Orthop Trauma Surg. 2015;135(l):19-28. doi: 10.1007/s00402-014-2122-5.
- Yang B., Li H., Zhang T., He X., Xu S. The incidence of adjacent segment degeneration after cervical disc arthroplasty (CDA): a meta analysis of randomized controlled trials. PLoS One. 2012;7(4):e35032. doi: 10.1371/joumal.pone.0035032.
- Hisey M.S., Bae H.W., Davis R.J., Gaede S., Hoffman G., Kim K.D. et al. Prospective, randomized comparison of cervical total disk replacement versus anterior cervical fusion: results at 48 months followup. ; Spinal Disord Tech. 2015;28(4):E237-243. doi: 10.1097/BSD.0000000000000185.
- Phillips F.M., Geisler F.H., Gilder K.M., Reah C., Howell K.M., McAfee P.C. Long-term outcomes of the US FDA IDE prospective, randomized controlled clinical trial comparing PCM cervical disc arthroplasty with anterior cervical discectomy and fusion. Spine (Phila Pa 1976). 2015;40(10):674-683. doi: 10.1097/BRS.0000000000000869.
- Burkus J.K., Traynelis V.C., Haid R.W. Jr., Mummaneni P.V. Clinical and radiographic analysis of an artificial cervical disc: 7-year follow-up from the Prestige prospective randomized controlled clinical trial: Clinical article. / Neurosurg Spine. 2014;21(4): 516-528. doi: 10.3171/2014.6.SPINE13996.
- Davis R.J., Kim K.D., Hisey M.S., Hoffman G.A., Bae H.W., Gaede S.E. et al. Cervical total disc replacement with the Mobi-C cervical artificial disc compared with anterior discectomy and fusion for treatment of 2-level symptomatic degenerative disc disease: a prospective, randomized, controlled multicenter clinical trial: clinical article. J Neurosurg Spine. 2013;19(5):532- 545. doi: 10.3171/2013.6.SPINE12527.
- Nunley P.D., Jawahar A., Kerr E.J.3rd, Gordon C.J., Cavanaugh D.A., Birdsong E.M., et al. Factors affecting the incidence of symptomatic adjacent-level disease in cervical spine after total disc arthroplasty: 2- to 4-year follow-up of 3 prospective randomized trials. Spine (Phila Pa 1976). 2012;37(6):445-451. doi: 10.1097/BRS.0b013e31822174b3.
- Yin S., Yu X., Zhou S., Yin Z., Oiu Y. Is cervical disc arthroplasty superior to fusion for treatment of symptomatic cervical disc disease? A meta-analysis. Clin Orthop Relat Res. 2013;471(6):1904-1919. doi: 10.1007/S11999-013-2830-0.
- Lei S., Ning G.-Z., Tang Y, Wang Z., Luo Z.-J., Zhou Y. Discover cervical disc arthroplasty versus anterior cervical discectomy and fusion in symptomatic cervical disc diseases: A meta-analysis. PLoS One. 2017;12(3):e0174822. doi: 10.1371/joumal.pone.0174822.
- Yi S., Kim K.N., Yang M.S., Yang J.W., Kim H., Ha Y. et al. Difference in occurrence of heterotopic ossification according to prosthesis type in the cervical artificial disc replacement. Spine (Phila Pa 1976). 2010;35(16):1556- 1561. doi: 10.1097/BRS.0b013e3181c6526b.
- Qi M., Chen H., Cao R, Tian Y, Yuan W. Incidence and risk factors analysis of heterotopic ossification after cervical disc replacement. Chin Med J (Engl). 2014;127(22):3871-3875.
Supplementary files
