MORPHOFUNCTIONAL STATUS OF REGIONAL LYMPH NODES IN CONDITIONS OF INTRAMEDULLARY OSTEOSYNTHESIS BY RETAINERS WITH COAT BASED ON SUPERHARD COMPOUNDS

Objective: to evaluate the morphofunctional state of the popliteal lymph nodes of the operated and intact pelvic rabbit limbs in conditions of intramedullary fixation of the tibia fracture with the implant coated with titanium nitride and hafnium. A morphological study of two groups of experimental animals was conducted. Osteoclasis of tibia and subsequent osteosynthesis with medical steel needles coated with and without titanium nitride and hafnium was made. In the lymph nodes of the animals in the comparison group both inflammatory (acute and chronic lymphadenitis) and immunomorfologycal (hyperplasia of T-and B-dependent areas, sinus histiocytosis) reactions were observed, with the latter being more common in the operated limb, and the inflammatory - in the intact one. The obtained data have proved the feasibility of using metal structures coated with nitrides of group IV metals (titanium and hafnium) for external osteosynthesis.

интрамедуллярный остеосинтез, лимфатические узлы, имплантаты с биоинертным покрытием, intramedullary osteosynthesis, lymph nodes, implants with bioinert coating