EXPERIMENTAL ESTIMATION OF THE DEMINERALIZED BONE ALLOGRAFTS MADE BY TECHNOLOGY OF CITO

Yu. B. Yurasova; Юрасов Ю. Б.; M. V. Lekishvili; Лекишвили М. В.; A. Yu. Ryabov; Рябов А. Ю.; G. P. Ter-Asaturov; Тер-Асарутов Г. П.; A. S. Pankratov; Панкратов А. С.; A. G. Khamidov; Хамидов А. Г.; A. T. Bigvava; Бигвава А. Т.

doi:10.21823/2311-2905-2010-0-1-146-149

EXPERIMENTAL ESTIMATION OF THE DEMINERALIZED BONE ALLOGRAFTS MADE BY TECHNOLOGY OF CITO

Authors: Yurasova Y.B.¹, Lekishvili M.V.², Ryabov A.Y.³, Ter-Asaturov G.P.⁴, Pankratov A.S.⁵, Khamidov A.G.⁶, Bigvava A.T.⁴
Affiliations:
1. Российская детская клиническая больница
2. ФГУ «ЦИТО им. Н.Н. Приорова»
3. ГУ «МОНИКИ им. М.Ф. Владимирского»
4. Московская медицинская академия им. И.М. Сеченова
5. Российский государственный медицинский университет
6. ФГУ «НКЦ оториноларингологии Росздрава»
Issue: Vol 16, No 1 (2010)
Pages: 146-149
Section: MATERIALS OF THE SCIENTIFIC AND PRACTICAL CONFERENCE
URL: https://journal.rniito.org/jour/article/view/507
DOI: https://doi.org/10.21823/2311-2905-2010-0-1-146-149
ID: 507

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Abstract

Research is devoted an experimental estimation of osteoinductive properties of demineralized bone implants (DBA) made on technology CITO with use of lyophilization and radiating sterilization by stream of fast electrons. As experimental animals, white rats on ectopic osteogenesis model for a period of 40 days and rabbits to which DBA implanted into defect of the jaw with terms of experiment 10, 20, 30, 60 and 90 days have been chosen. Results of morphological researches testified to absence of toxicity, presence of high indicators of biointegration and osteoinductance studied DBA. The offered technology of processing of a bone tissue allows to keep biological activity of tissues and to receive biological materials with the expressed plastic properties. Obtained among other data were the bases for the decision of use of these materials in clinic of different bone pathologies.

Keywords

demineralized bone allografts, experimental morphological researches, osteoinductance

References

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Савельев В.И. Получение и сохранение деминерализованной костной ткани для клинического применения/В.И. Савельев//Деминерализованные костные трансплантаты и их использование в восстановительной хирургии: сб. науч. трудов. -СПб., 1996. -С. 3-12.
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Von Versen R. The peracetic acid/low pressure cold sterilization -A new method to sterilize corticocancellous bone and soft tissue/R. Von Versen, R. Starke//J. Exp. Chir. Transplant. Künstl. Org. -1989. -Bd. 22, H. 1. -P. 18-21.

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EXPERIMENTAL ESTIMATION OF THE DEMINERALIZED BONE ALLOGRAFTS MADE BY TECHNOLOGY OF CITO

Full Text

Abstract

Keywords

About the authors

Yu. B. Yurasova

M. V. Lekishvili

A. Yu. Ryabov

G. P. Ter-Asaturov

A. S. Pankratov

A. G. Khamidov

A. T. Bigvava

References

Supplementary files

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