THE INFLUENCE OF VARIOUS FACTORS ON BLOOD LOSS IN PATIENTS UNDERGOING TOTAL HIP REPLACEMENT

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Abstract

Objective: to assess the influence of various factors on blood loss and blood parameters in the postoperative period in patients undergoing hip replacement surgery with and without tranexamic acid. Material and methods. The operations of primary and revision hip arthroplasty were performed in 646 patients with various pathology of the hip by two surgery teams. Patients were divided into two groups: with the use the tranexamic acid - 284 and without its application - 362. We determined the amount of intraoperative blood loss, blood parameters (hemoglobin, red blood cells, platelets) before surgery and in the first, third and sixth days after the operation. Also the analysis of drainage system influence is carried out. Results. The tranexamic acid application during total hip arthroplasty allows to reduce intraoperative blood loss, to optimize the process of normalization red blood in the postoperative period. The renunciation of wound drainage decreased the total amount of blood loss on average 2.2 times and respectively, the need for blood transfusions.

About the authors

R. M. Tikhilov

The Vreden’s Russian Research Institute of Traumatology and Orthopedics St.-Petersburg

Author for correspondence.
Email: info@rniito.org
Russian Federation

A. B. Serebryakov

Medical-Rehabilitation Center Moscow

Email: cvmr@bk.ru
Russian Federation

I. I. Shubnyakov

The Vreden’s Russian Research Institute of Traumatology and Orthopedics St.-Petersburg

Email: shubnyakov@mail.ru
Russian Federation

D. G. Pliev

The Vreden’s Russian Research Institute of Traumatology and Orthopedics St.-Petersburg

Email: plievd@gmail.com
Russian Federation

V. A. Shilnikov

The Vreden’s Russian Research Institute of Traumatology and Orthopedics St.-Petersburg

Email: vreden11@rambler.ru
Russian Federation

A. O. Denisov

The Vreden’s Russian Research Institute of Traumatology and Orthopedics St.-Petersburg

Email: med-03@yandex.ru
Russian Federation

A. A. Myasoedov

The Vreden’s Russian Research Institute of Traumatology and Orthopedics St.-Petersburg

Email: myasoedov_alexei@mail.ru
Russian Federation

A. A. Boyarov

The Vreden’s Russian Research Institute of Traumatology and Orthopedics St.-Petersburg

Email: bojaroffaa@mail.ru
Russian Federation

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