COMPARATIVE ANALYSIS OF BIOCHEMICAL PARAMETERS OF MUSCLE TISSUE ALTERATION DEPENDING ON APPROACHES FOR TOTAL HIP ARTHROPLASTY

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Abstract

The results of the comparative analysis of biochemical alterations of muscle tissue in the blood serum of patients who underwent primary total hip replacement. In this study, we consider the data of 75 patients who underwent total hip arthroplasty (75 operations) from November 2010 to April 2012 to analyze the data was divided into 3 groups of patients: the first - using a minimally invasive technique MIS AL (22 operations), the second - with the use of the modified approach Muller (pending on the invention) - (29 operations), and the third - with approach by Hardinge (26 operations). The levels of glutamic oxaloacetic transaminase, creatinine phosphokinase, lactate dehydrogenase, myoglobin, creatinine, and C-reactive proteine in serum were determined preoperatively and at 3, 5, 7, 9 days after surgery. CRP included in the study as an indicator of non-specific inflammation of the tissues. When comparing the biochemical indicators in three types of approaches to the hip joint, the highest increase in GOAT, LDH, CPK, CRP, and myoglobin was detected at surgery approach by Hardinge. The results of this study may indicate a decrease in the degree of tissue trauma during surgery using a minimally-invasive approaches, which is characterized by the retention of attachment to the middle gluteal muscle of the femur.

About the authors

R. M. Tikhilov

Vreden Russian Research Institute of Traumatology and Orthopedics

Author for correspondence.
Email: info@rniito.org
Russian Federation

D. V. Andreev

Vreden Russian Research Institute of Traumatology and Orthopedics

Email: dandreef@gmail.com
Russian Federation

M. Y. Goncharov

Vreden Russian Research Institute of Traumatology and Orthopedics

Email: goncharov71@list.ru
Russian Federation

O. V. Shneyder

Vreden Russian Research Institute of Traumatology and Orthopedics

Email: ovshnejder@rniito.ru
Russian Federation

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