Biologically rational ways of bone mass loss prophylaxis and treatment

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Abstract

Aim. Based on own and literature date to define biologically rational elements of complex approach to bone mass loss prophylaxis and treatment. Nowadays there are two points of view regarding bone mass loss prophylaxis and treatment. The first favor pharmaceuticals as a basic and physical exercises as additional. According to the second, therapeutic and prophylactic significance of physical exercises in maintenance and development of structural and functional capacities of musculoskeletal system is fundamental. The latter approach correspond to evolutionary formed biological model in that muscles act upon levers - bones that connected by means of joints and provide the movement of the body against gravity. The present work from pathogenethically point of view establish the systemic approach to the bone mass loss prophylaxis and treatment. It is based on physical exercises while additional pharmacotherapy that should aim for optimization of regulatory function of bone cells, first of all osteocytes providing for adaptational reorganisation of bone structures.

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About the authors

A. S. Avrunin

Vreden Russian Research Institute of Traumatology and Orthopedics

Author for correspondence.
Email: a_avrunin@mail.ru
senior researcher of the scientific department of the diagnosis and treatment of musculoskeletal system diseases and injuries Russian Federation

A. A. Doktorov

All-Russian Research Institute on Medicinal and Aromatic Plant

Email: fake@neicon.ru
professor the head of morphology department Russian Federation

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