<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Traumatology and Orthopedics of Russia</journal-id><journal-title-group><journal-title xml:lang="en">Traumatology and Orthopedics of Russia</journal-title><trans-title-group xml:lang="ru"><trans-title>Травматология и ортопедия России</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2311-2905</issn><issn publication-format="electronic">2542-0933</issn><publisher><publisher-name xml:lang="en">Vreden National Medical Research Center of Traumatology and Orthopedics</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">728</article-id><article-id pub-id-type="doi">10.21823/2311-2905-2017-23-2-66-73</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Case Reports</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Случаи из практики</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="zh"><subject>Case Reports</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">CONTINUOUS THROMBOPROPHYLAXIS DURING SURGICAL TREATMENT OF PATIENT WITH POLYTRAUMA IN A MULTIDISCIPLINARY HOSPITAL (CASE REPORT)</article-title><trans-title-group xml:lang="ru"><trans-title>ПРИ ХИРУРГИЧЕСКОМ ЛЕЧЕНИИ ПАЦИЕНТА С ПОЛИТРАВМОЙ В УСЛОВИЯХ МНОГОПРОФИЛЬНОГО СТАЦИОНАРА (СЛУЧАЙ ИЗ ПРАКТИКИ)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Belenky</surname><given-names>I. G.</given-names></name><name xml:lang="ru"><surname>Беленький</surname><given-names>И. Г.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Igor G. Belenky  – Dr.  Sci.  (Med.),   Associate  Professor of Department of Traumatology and  Orthopedics of Pavlov First  SPSMU; the  head of Trauma Department N 1.</p><p>6-8, ul. L’va Tolstogo, St. Petersburg, 197022; 4, Prospect Solidarnosti, St. Petersburg, 193312</p></bio><bio xml:lang="ru"><p>Беленький  Игорь Григорьевич – доктор  медицинских наук,  доцент кафедры травматологии и ортопедии ПСПГМУ; заведующий     травматологическим    отделением     №    1 СПб.</p><p>Ул. Льва Толстого, д. 6-8, Санкт-Петербург, 197022; Пр-т Солидарности, д. 4, Санкт-Петербург, 193312</p></bio><email>belenkiy.trauma@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Sergeev</surname><given-names>G. D.</given-names></name><name xml:lang="ru"><surname>Сергеев</surname><given-names>Г. Д.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Gennadii   D.  Sergeev  –  Orthopedic Surgeon,   Trauma Department N 1.</p><p>4, Prospect Solidarnosti, St. Petersburg, 193312</p></bio><bio xml:lang="ru"><p>Сергеев Геннадий Дмитриевич  – врач травматологортопед  травматологического отделения № 1 СПб.</p><p>Пр-т Солидарности, д. 4, Санкт-Петербург, 193312</p></bio><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Pavlov First St. Petersburg State Medical University</institution></aff><aff><institution xml:lang="ru">ГБОУ ВПО «Первый Санкт-Петербургский государственный медицинский университет им. акад. И.П. Павлова» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Aleksandrov Hospital</institution></aff><aff><institution xml:lang="ru">СПб ГБУЗ «Александровская больница»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2017-07-01" publication-format="electronic"><day>01</day><month>07</month><year>2017</year></pub-date><volume>23</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>66</fpage><lpage>73</lpage><history><date date-type="received" iso-8601-date="2017-07-01"><day>01</day><month>07</month><year>2017</year></date><date date-type="accepted" iso-8601-date="2017-07-01"><day>01</day><month>07</month><year>2017</year></date></history><permissions><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://journal.rniito.org/jour/article/view/728">https://journal.rniito.org/jour/article/view/728</self-uri><abstract xml:lang="en"><p>The paper presents  a clinical case of a staged surgical treatment according  to damage control  protocol  for a patient with multiple limb fractures, sternum  trauma as well as brain injury due to traffic accident. Following temporary external fixation during emergency treatment, 6 internal fixation procedures were performed on the patient during three surgical sessions. 4,5 months  postoperatively the authors  observed  consolidation of all fractures  with good restoration of joints function. Prophylaxis of venous thromboembolic events included low molecular heparins administration prior to the first and consequent surgical  sessions as well as oral anticoagulants during  intervals between  procedures and for extended prophylaxis. Apart from medicinal prophylaxis  the authors  utilized therapeutic exercises at all treatment stages.</p></abstract><trans-abstract xml:lang="ru"><p>Описан  клинический случай этапного хирургического лечения  по протоколу  контроля повреждений пациента после дорожно-транспортного происшествия с множественными переломами костей конечностей, грудины и черепно-мозговой травмой.  После  предварительной наружной  фиксации переломов  на этапе оказания экстренной  помощи пациенту  в течение трех операционных сессий выполнено  6 операций  внутреннего  остеосинтеза. Через 4,5 мес. после травмы констатировано сращение всех переломов с хорошим восстановлением функции суставов конечностей.  Схема медикаментозной профилактики венозных тромбоэмболических осложнений (ВТО) заключалась в том, что до первой операционной сессии, а также перед последующими операционными сессиями  применяли низкомолекулярные гепарины,  а в промежутках между операционными сессиями  и с целью продленной профилактики – пероральные антикоагулянты. Кроме того, на всех этапах лечения применяли ЛФК как средство немедикаментозной профилактики ВТО.</p></trans-abstract><kwd-group xml:lang="en"><kwd>polytrauma</kwd><kwd>damage control</kwd><kwd>prophylaxis of venous thromboembolic events</kwd><kwd>oral anticoagulants</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>политравма</kwd><kwd>тактика контроля повреждений</kwd><kwd>профилактика венозных тромбоэмболических осложнений</kwd><kwd>пероральные антикоагулянты</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>1. Багненко С.Ф., Минуллин И.П., Чикин А.Е., Разумный Н.В., Фисенко В.С. Совершенствование медицинской помощи пострадавшим при дорожно-транспортных происшествиях. Вестник Росздравнадзора. 2013;(5):25-30.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>2. Беленький И.Г., Кутянов Д.И., Хоминец В.В. Анализ лечения пострадавших с переломами длинных костей конечностей в условиях городского многопрофильного стационара. Профилактическая и клиническая медицина. 2011;(2-2):104-106.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>3. Профилактика венозных тромбоэмболических осложнений в травматологии и ортопедии. Российские клинические рекомендации. Травматология и ортопедия России. 2012;(1)Приложение:1-24.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>4. Российские клинические рекомендации по диагностике, лечению и профилактике венозных тромбоэмболических	осложнений (ВТэО). Флебология. 2015;9(4-2):1-52.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>5. Bates P., Parker P., McFadyen I., Pallister I. Demystifying damage control in musculoskeletal trauma. Ann R Coll Surg Engl. 2016;98(5):291-294. DOI: 10.1308/rcsann.2016.0111.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>6. Bone L.B., Johnson K.D., Weigelt J., Scheinberg R. Early versus delayed stabilization of fractures: a prospective randomized study. J Bone Joint Surg Am. 1989;71(3):336-340. DOI: 10.2106/00004623-198971030-00004.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>7. Bosse M.J., Mackenzie E.J., Riemer B.L., Brumback R.J., Mccarthy M.L., Burgess R., Gens D.R., Yasui Y. Adult respiratory distress syndrome, pneumonia, and mortality following thoracic injury and a femoral fracture treated either with intramedullary nailing with reaming or with a plate. A comparative study. J Bone Joint Surg Am. 1997;79: 799-809. DOI:10.2106/00004623-199706000-00001.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>8. Boulanger B.R., Stephen D., Brennemann F.D. Thoracic trauma and early intramedullary nailing of femur fractures: are we doing harm? J Trauma. 1997;43(1):24-28. DOI: 10.1097/00005373-199707000-00008.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>9. Bradford D.S., Foster R.R., Nossel H.L. Coagulation alterations, hypoxemia, and fat embolism in fracture patients. J Trauma. 1970;10(4):307-321. DOI: 10.1097/00005373-197004000-00004.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>10. Giannoudis P.V. Aspects of current management. Surgical priorities in damage control in polytrauma. J Bone Joint Surg Br. 2003;85(4):478-483. DOI: 10.1302/0301-620X.85B4.14217.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>11. Giannoudis P.V., Abbott C., Stone M., Bellamy M.C., Smith R.M. Fatal systemic inflammatory response syndrome following early bilateral femoral nailing. Intensive Care M. 1998;24(6):641-642. DOI: 10.1007/s001340050631.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>12. Giannoudis P.V., Smith R.M., Bellamy M.C, Morrison J.F., Dickson R.A., Guillou P.J. Stimulation of the inflammatory system by reamed and unreamed nailing of femoral fractures: an analysis of the second hit. J Bone Joint Surg Br. 1999;81(2):356-361. DOI: 10.1302/0301-620x.81b2.8988.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>13. Gruen R.L, Jurkovich G.J., Mcintyre L.K., Foy H.M., Maier R.V. Patterns of errors contributing to trauma mortality: lessons learned from 2,594 deaths. Ann Surg. 2006;244(3):371-380. DOI: 10.1097/01.sla.0000234655.83517.56.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>14. Guyatt G.H., Akl E.A., Crowther M., Gutterman D.D., Schuünemann H.J. Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice guidelines. Chest. 2012;141(2 Suppl):7-47. DOI: 10.1378/chest.1412S3.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>15. Hussmann B., Lendemans S. Pre-hospital and early inhospital management of severe injuries: Changes and trends. Injury. 2014;45(Suppl 3):39-42. DOI: 10.1016/j.injury.2014.08.016.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>16. Lassen M.R., Borris L.C., Nakov R.L. Use of lowmolecularweight heparin reviparin to prevent deep-vein thrombosis after leg injury requiring immobilization. N Eng J Med. 2002;347(10):726-730. DOI: 10.1056/NEJMoa011327.</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>17. O’toole R.V., O’brien M., Scalea T.M., Habashi N., Pollak A.N., Turen C.H. Resuscitation before stabilization of femoral fractures limits acute respiratory distress syndrome in patients with multiple traumatic injuries despite low use of damage control orthopedics. J Trauma. 2009;67(5): 1013-1021. DOI: 10.1097/TA.0b013e3181b890be.</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>18. Pape H.-C., Auf’m’Kolk M., Paffrath T., Regel G., Sturm J.A., Tscherne H. Primary intramedullary femur fixation in multiple trauma patients with associated lung contusion: a cause of post-traumatic ARDS? J Trauma. 1993;34(4):540-548. DOI: 10.1097/00005373-199304000-00010.</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>19. Pape H.-C., Van Griensven M., Rice J., Gansslen A., Hildebrand F., Zech S., Winny M., Lichtinghagen R., Krettek C. Major secondary surgery in blunt trauma patients and perioperative cytokine liberation: determination of the clinical relevance of biochemical markers. J Trauma. 2001;50(6):989-1000. DOI: 10.1097/00005373-200106000-00004.</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>20. Ratto N. Early Total Care versus Damage Control: Current Concepts in the Orthopedic Care of Polytrauma Patients. ISRN Orthopedics. 2013;2013:329452. DOI: 10.1155/2013/329452.</mixed-citation></ref><ref id="B21"><label>21.</label><mixed-citation>21. Renne J., Wuthier R., House E., Cancro J.C., Hoaglund	F.T. Fat macroglobulemia caused by fractures or total hip replacement. J Bone Joint Surg Am. 1978;60-(5):613-618. DOI: 10.2106/00004623-197860050-00005.</mixed-citation></ref><ref id="B22"><label>22.</label><mixed-citation>22. Roberts C.S., Pape H.-C., Jones A.L., Malkani A.L., Rodriguez J.L., Giannoudis P.V. Damage control orthopaedics: Evolving concepts in the treatment of patients who have sustained orthopaedic trauma. J Bone Joint Surg Am. 2005;87(2):434-449. DOI: 10.2106/00004623-200502000-00030.</mixed-citation></ref><ref id="B23"><label>23.</label><mixed-citation>23. Rotondo M.Z., Schwab C.W., Mcgonigal M.D., Phillips G.R. 3rd, Fruchterman T.M., Kauder D.R., Latenser B.A., Angood P.A. Damage control: an approach for improved survival in exsanguinating penetrating abdominal injury. J Trauma. 1993;35(3):375-382. DOI: 10.1097/00005373-199309000-00008.</mixed-citation></ref><ref id="B24"><label>24.</label><mixed-citation>24. Sturm J.A., Wisner D.H., Oestern H.J., Kant C.J., Tscherne H., Creutzig H. Increased lung capillary permeability after trauma: a prospective clinical study. J Trauma. 1986;26(5):409-418. DOI: 10.1097/00005373-198605000-00001.</mixed-citation></ref><ref id="B25"><label>25.</label><mixed-citation>25. Wang A.M., Yin X., Sun H.Z., DU Q.Y., Wang Z.M. Damage control orthopaedics in 53 cases of severe polytrauma who have mainly sustained orthopaedic trauma. Chin J Traumatol. 2008;11(5):283-287. DOI: 10.1016/s1008-1275(08)60057-7.</mixed-citation></ref><ref id="B26"><label>26.</label><mixed-citation>26. Yenna Z.C., Roberts C. Thromboprophylaxis after multiple trauma: what treatment and for how long? Injury. 2009;40 (Suppl 4):90-94. DOI:10.1016/j.injury.2009.10.042.</mixed-citation></ref></ref-list></back></article>
