Traumatology and Orthopedics of RussiaTraumatology and Orthopedics of Russia2311-29052542-0933Vreden National Medical Research Center of Traumatology and Orthopedics39610.21823/2311-2905-2011-0-1-61-66THE INFLUENCE OF COLD PLASMA ABLATION ON HUMAN AND ANIMAL KNEE JOINT CARTILAGEBogatovV. B.vicbogatov@rambler.ruMatveevaO. V.fake@neicon.ruPetrovA. B.fake@neicon.ru3003201117161660311201603112016Copyright © ,<p>Cold plasma ablation is widely used in knee arthroscopy during past decade. We studied its influence on knee joint cartilage in a human in vitro and in dogs in vivo. Histomorphological study was performed in a human cartilage right after the exposition of CPA. In animals MRI and morphological study were performed after three months of exposition of CPA. It was shown that CPA was able to cause immediate changes of collagen in the human cartilage in vitro and also death of chondrocytes in animal in vivo after three months. The depth of necrosis of the cartilage in animal was significantly deeper the subhondral bone.</p>knee jointcartilagecold plasma ablationколенный суставхрящхолодно-плазменная аблация[1. Allen, R.T. Meniscal debridement with an arthroscopic radiofrequency wand versus an arthroscopic shaver: comparative effects on menisci and arthicular cartilage / R.T. Allen [et al.] // Arthroscopy. – 2006. – Vol. 22, N 3. – P. 385–393.][2. Bonutti, P.M. Osteonecrosis of the knee after laser or radiofrequency-assisted arthroscopy / P.M. Bonutti [et al.] // J. Bone Joint Surg. – 2006. – Vol. 88-A. – P. 69–75.][3. Caffey, S. Effects of radiofrequency energy on human articular cartilage: an analysis of 5 systems / S. Caffey [et al.] // Am. J. Sports Med. – 2005. – Vol. 33. – P. 1035–1039.][4. Cook, J.L. Assessment of cellular, biochemical and histological effects of bipolar radiofrequency treatment of canine articular cartilage / J.L. Cook [et al.] // Am. J. Vet. Res. – 2004. – Vol. 65. – P. 604–609.][5. Green, L.M. In vitro effects of 3 common arthroscopic instruments on articular cartilage / L.M. Green [et al.] // Arthroscopy. – 2006. – Vol. 22, N 3. – P. 300–307.][6. Kaab, M.J. Monopolar radiofrequency treatment of partial-thickness cartilage defects in the sheep knee joint leads to extended cartilage injury / M.J. Kaab [et al.] // Am. J. Sports Med. – 2005. – Vol. 33, N 10. – P. 1472–1478.][7. Lu, Y. Thermal chondroplasty with radiofrequency energy. An in vitro comparison of bipolar and monopolar radiofrequency devices / Y. Lu [et al.] // Am. J. Sports Med. – 2001. – Vol. 29. – P.42–49.][8. Lu, Y. Thermal chondroplasty with bipolar and monopolar radiofrequency energy: effect of treatment time on chondrocite death and surface contouring / Y. Lu [et al.] // Arthroscopy. – 2002. – Vol. 18, N 7. – P. 779–788.][9. Perry, J.J. Anterior and posterior cruciate ligament rupture after thermal treatment / J.J. Perry, L.D. Higgins // Arthroscopy. – 2000. – Vol.16. – P.732–736.][10. Polousky, J.D. Electrosurgical methods for arthroscopic meniscectomy: a review of literature / J.D. Polousky, T.P. Hedman, C.T. Vagness // Arthroscopy. – 2000. – Vol. 16. – P. 813–821.][11. Sherk H.H. Electromag netic surgical devices in orthopedics / H.H. Sherk [et al.] // J. Bone Joint Surg. – 2002. – Vol. 84-A. – P.675–681.][12. Yasura, K. Mechanical and biochemical effect of monopolar radiofrequency energy on human articular cartilage: an in vitro study / K. Yasura [et al.] // Am. J. Sports Med. – 2006. – Vol. 34, N 8. – P. 1322–1327.]