The article deals with basic findings derived from annual investigation, held by Coordination-methodic Center specialized in “orthopedics and traumatology”. The analysis of dynamics of main indices of incidence of trauma and musculoskeletal diseases in adult population was based upon official findings of federal statistic monitoring of condition and work of specialized medical service. The evaluation of structure, dynamics and work of the hospital and out-patient service was made in compare with incidence dynamics of trauma and musculoskeletal diseases. Generally Saint-Petersburg characterized with high level of traumatism of population with tendency to decreasing, big part of severe skeletal injuries of population, increasing of number of patients with chronic diseases of locomotor system, big part of yang and middle aged patients with temporary lost of possibility to work because of injuries, high level of mortality (with prevalence of men) and tendency to decreasing. Trends of processes of traumatology and orthopedic care system reflects increasing of volume of specialized trauma service for city population as in ambulatory as in hospital links, increasing of intensity of using of traumatology and orthopedic beds in city hospitals, decreasing of deaths caused of injuries in city hospitals, increasing of number of surgical interventions of locomotor system and decreasing of postoperative hospital mortality.