Traumatology and Orthopedics of RussiaTraumatology and Orthopedics of RussiaТравматология и ортопедия России2311-29052542-0933Vreden National Medical Research Center of Traumatology and Orthopedics179710.17816/2311-2905-1797FOR PRACTICIONERSДЛЯ ПРАКТИЧЕСКИХ ВРАЧЕЙReview ArticleDiagnosis of Deep Periprosthetic Infection of the HipДиагностика глубокой перипротезной инфекции тазобедренного суставаhttps://orcid.org/0000-0001-5753-8926MurylevValery Yu.МурылевВалерий Юрьевич
Russian Federation

Dr. Sci (Med.), Professor

д-р мед. наук, профессор

nmuril@yandex.ruhttps://orcid.org/0000-0003-4490-2922RudnevAlexander I.РудневАлександр Игоревич
Russian Federation
ruda310895@gmail.comhttps://orcid.org/0000-0001-6700-0222KukovenkoGrigory A.КуковенкоГригорий Андреевич
Russian Federation

Cand. Sci. (Med.)

канд. мед. наук

gkukovenko@gmail.comhttps://orcid.org/0000-0002-0217-2434ElizarovPavel M.ЕлизаровПавел Михайлович
Russian Federation

Cand. Sci. (Med.)

канд. мед. наук

elizarov_07@mail.ruhttps://orcid.org/0000-0002-3933-672XMuzychenkovAlexey V.МузыченковАлексей Владимирович
Russian Federation

Cand. Sci. (Med.)

канд. мед. наук

amuzychenkov@inbox.ruhttps://orcid.org/0000-0001-7599-7472AlekseevSemyon SergeevichАлексеевСемён Сергеевич
Russian Federation
semen.alekseev.92@mail.ruSechenov First Moscow State Medical University (Sechenov University)ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет)», Минздрава РоссииBotkin Moscow City HospitalГБУЗ «Городская клиническая больница им. С.П. Боткина» Департамента здравоохранения г. МосквыBotkin Moscow City HospitalГБУЗ «Городская клиническая больница им. С.П. Боткина» Департамента здравоохранения г. МосквыSechenov First Moscow State Medical University (Sechenov University)ФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова (Сеченовский Университет)», Минздрава России230920222831231351106202212082022Copyright ©; 2022, Murylev V.Y., Rudnev A.I., Kukovenko G.A., Elizarov P.M., Muzychenkov A.V., Alekseev S.S.Copyright ©; 2022, Мурылев В.Ю., Руднев А.И., Куковенко Г.А., Елизаров П.М., Музыченков А.В., Алексеев С.С.Copyright ©; 2022, Murylev V., Rudnev A., Kukovenko G., Elizarov P., Muzychenkov A., Alekseev S.2022Murylev V.Y., Rudnev A.I., Kukovenko G.A., Elizarov P.M., Muzychenkov A.V., Alekseev S.S.Мурылев В.Ю., Руднев А.И., Куковенко Г.А., Елизаров П.М., Музыченков А.В., Алексеев С.С.Murylev V., Rudnev A., Kukovenko G., Elizarov P., Muzychenkov A., Alekseev S.https://creativecommons.org/licenses/by/4.0https://journal.rniito.org/jour/article/view/1797

Periprosthetic infection (PJI) is one of the most frequent and devastating complications of total hip arthroplasty (THA). Early and accurate diagnosis of PJI allows timely initiation of treatment. Various diagnostic tools and algorithms for hip PJI diagnosis are described. The available serum (ESR, CRP, D-dimer, etc.) and synovial (alpha-defensin, leukocyte esterase, D-lactate) biomarkers are listed, as well as their combinations for the purpose of PJI verification. Combined serum and synovial tests can significantly improve the efficiency of PJI hip diagnosis.

Перипротезная инфекция (ППИ) является одним из наиболее частых и разрушительных осложнений эндопротезирования тазобедренного сустава (ТБС). Ранняя и точная диагностика ППИ позволяет своевременно начать лечение. Описаны различные диагностические инструменты и алгоритмы диагностики ППИ ТБС. Перечислены имеющиеся сывороточные (СОЭ, СРБ, D-димер и др.) и синовиальные (альфа-дефенсин, лейкоцитарная эстераза, D-лактат) биомаркеры, а также их комбинации с целью верификации ППИ. Объединение сывороточных и синовиальных тестов позволяет значительно повысить эффективность диагностики ППИ ТБС.

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