Traumatology and Orthopedics of RussiaTraumatology and Orthopedics of RussiaТравматология и ортопедия России2311-29052542-0933Vreden National Medical Research Center of Traumatology and Orthopedics1710.21823/2311-2905-17ReviewsОбзорыReviewsUnknownBiologically rational ways of bone mass loss prophylaxis and treatmentБИОЛОГИЧЕСКИ ЦЕЛЕСООБРАЗНЫЕ ПУТИ ПРОФИЛАКТИКИ И ЛЕЧЕНИЯ ПОТЕРИ КОСТНОЙ МАССЫAvruninA. S.АврунинА. С.
Russian Federation

senior researcher of the scientific department of the diagnosis and treatment of musculoskeletal system diseases and injuries

д-р мед. наук старший научный сотрудник

a_avrunin@mail.ruDoktorovA. A.ДокторовА. А.
Russian Federation

professor the head of morphology department

д-р мед. наук профессор заведующий отделом морфологии

Vreden Russian Research Institute of Traumatology and OrthopedicsФГБУ «Российский научно-исследовательский институт травматологии и ортопедии им. Р.Р. Вредена»All-Russian Research Institute on Medicinal and Aromatic PlantФГБНУ «Всероссийский институт лекарственных и ароматических растений»221220152141311432406201624062016Copyright ©; 2015,Copyright ©; 2015,2015https://journal.rniito.org/jour/article/view/17

Aim. Based on own and literature date to define biologically rational elements of complex approach to bone mass loss prophylaxis and treatment. Nowadays there are two points of view regarding bone mass loss prophylaxis and treatment. The first favor pharmaceuticals as a basic and physical exercises as additional. According to the second, therapeutic and prophylactic significance of physical exercises in maintenance and development of structural and functional capacities of musculoskeletal system is fundamental. The latter approach correspond to evolutionary formed biological model in that muscles act upon levers - bones that connected by means of joints and provide the movement of the body against gravity. The present work from pathogenethically point of view establish the systemic approach to the bone mass loss prophylaxis and treatment. It is based on physical exercises while additional pharmacotherapy that should aim for optimization of regulatory function of bone cells, first of all osteocytes providing for adaptational reorganisation of bone structures.

Цель - на основании анализа литературы определить биологически целесообразные элементы комплексного подхода к профилактике и лечению потери костной массы. В настоящее время существует два взгляда на проблему профилактики и лечения потери костной массы. Согласно одному из них, основополагающим является использование фармацевтических препаратов, а роль физических упражнений рассматривается как вспомогательная. Согласно представителям второй школы, лечебная и профилактическая роль физических упражнений в поддержании и развитии структурно-функциональных возможностей скелетно-мышечной системы является основополагающей. Этот подход соответствует сформировавшейся в процессе эволюции биологической модели, в которой мышцы, воздействуя на рычаги-кости связанными между собой суставами, обеспечивают перемещения тела в пространстве гравитационного поля. В настоящей работе представлено патогенетическое обоснование комплексного подхода к профилактике и лечению потери костной массы. В его основе лежат физические упражнения, а дополнительное использование медикаментозных средств должно быть направлено на оптимизацию регулирующей функции костных клеток, в первую очередь остеоцитов, которые обеспечивают адаптивную реорганизацию костных структур.

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