<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Traumatology and Orthopedics of Russia</journal-id><journal-title-group><journal-title xml:lang="en">Traumatology and Orthopedics of Russia</journal-title><trans-title-group xml:lang="ru"><trans-title>Травматология и ортопедия России</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2311-2905</issn><issn publication-format="electronic">2542-0933</issn><publisher><publisher-name xml:lang="en">Vreden National Medical Research Center of Traumatology and Orthopedics</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1691</article-id><article-id pub-id-type="doi">10.17816/2311-2905-1691</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Case Reports</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Случаи из практики</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="zh"><subject>Case Reports</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Reccurence of Heterotopic Ossification as the Result of Total Hip Endoprosthesis Dislocation: A Case Report</article-title><trans-title-group xml:lang="ru"><trans-title>Рецидив гетеротопической оссификации в результате вывиха эндопротеза тазобедренного сустава: клинический случай</trans-title></trans-title-group><trans-title-group xml:lang="zh"><trans-title/></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3310-0799</contrib-id><contrib-id contrib-id-type="spin">1689-2611</contrib-id><name-alternatives><name xml:lang="en"><surname>Efimov</surname><given-names>Gleb A.</given-names></name><name xml:lang="ru"><surname>Ефимов</surname><given-names>Глеб Александрович</given-names></name><name xml:lang="zh"><surname></surname><given-names></given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>clinical resident</p></bio><bio xml:lang="ru"><p>ординатор</p></bio><email>glebefimovv@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2799-532X</contrib-id><name-alternatives><name xml:lang="en"><surname>Cherkasov</surname><given-names>Magomed A.</given-names></name><name xml:lang="ru"><surname>Черкасов</surname><given-names>Магомед Ахмедович</given-names></name><name xml:lang="zh"><surname></surname><given-names></given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Cand. Sci. (Med.)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><email>medik@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6435-7939</contrib-id><name-alternatives><name xml:lang="en"><surname>Goncharov</surname><given-names>Maksim Yu.</given-names></name><name xml:lang="ru"><surname>Гончаров</surname><given-names>Максим Юрьевич</given-names></name><name xml:lang="zh"><surname></surname><given-names></given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Cand. Sci. (Med.)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><email>goncharov71@list.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1813-3421</contrib-id><name-alternatives><name xml:lang="en"><surname>Efimov</surname><given-names>Nicolay N.</given-names></name><name xml:lang="ru"><surname>Ефимов</surname><given-names>Николай Николаевич</given-names></name><name xml:lang="zh"><surname></surname><given-names></given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Cand. Sci. (Med.)</p></bio><bio xml:lang="ru"><p>канд. мед. наук</p></bio><email>efimov-n-n@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Vreden National Medical Research Center of Traumatology and Orthopedics</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный медицинский исследовательский центр травматологии и ортопедии им. Р.Р. Вредена» Минздрава России</institution></aff><aff><institution xml:lang="zh"></institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2022-04-12" publication-format="electronic"><day>12</day><month>04</month><year>2022</year></pub-date><pub-date date-type="pub" iso-8601-date="2022-06-28" publication-format="electronic"><day>28</day><month>06</month><year>2022</year></pub-date><volume>28</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><issue-title xml:lang="zh"/><fpage>97</fpage><lpage>104</lpage><history><date date-type="received" iso-8601-date="2021-10-22"><day>22</day><month>10</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2022-04-04"><day>04</day><month>04</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2022, Efimov G.A., Cherkasov M.A., Goncharov M.Y., Efimov N.N.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2022, Ефимов Г.А., Черкасов М.А., Гончаров М.Ю., Ефимов Н.Н.</copyright-statement><copyright-statement xml:lang="zh">Copyright ©; 2022, Efimov G., Cherkasov M., Goncharov M., Efimov N.</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="en">Efimov G.A., Cherkasov M.A., Goncharov M.Y., Efimov N.N.</copyright-holder><copyright-holder xml:lang="ru">Ефимов Г.А., Черкасов М.А., Гончаров М.Ю., Ефимов Н.Н.</copyright-holder><copyright-holder xml:lang="zh">Efimov G., Cherkasov M., Goncharov M., Efimov N.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://journal.rniito.org/jour/article/view/1691">https://journal.rniito.org/jour/article/view/1691</self-uri><abstract xml:lang="en"><p><bold><italic>Background.</italic></bold> Heterotopic ossification (HO) is the formation of mature bone in soft tissues. HO in the hip area can be a consequence of both injury to the nervous system and local trauma. After total hip arthroplasty HO develops in 30% of cases.</p> <p><bold><italic>The aim of the study </italic></bold>is to demonstrate a rare clinical case of a recurrence of HO in patient after a primary total hip arthroplasty, accompanied by ankylosing.</p> <p><bold><italic>Case presentation.</italic></bold> A 32-year-old patient was admitted to the clinic for revision hip arthroplasty with a diagnosis «long-standing dislocation of the right hip joint endoprosthesis head, heterotopic ossification» 3 years after dislocation. During the surgery, there were difficulties with the sciatic nerve dissection, as well as the structures of the endoprosthesis. We removed all the ossifications that obstructed the dislocation of the endoprosthesis. The patient had sciatic nerve neuropathy on the right lower limb with lesions of the fibular and tibial nerves on the background of edema. The patient was discharged on the 21st day. The presented clinical case is interesting because the patient’s relapse could be caused by a combination of various risk factors. Taking into account the fact that the injury was received as a result of an accident and the patient had a fracture of the bones of the contralateral shin, it could be the effect of a local hip injury that aggravated the process.</p> <p><bold><italic>Conclusions.</italic></bold> This clinical observation highlights the importance of preventing possible complications after surgery and maintaining feedback with patients, especially those belonging to the high-risk group. It is likely that with adequate prevention of the HO formation and timely reduction of dislocation, the problems described in the article after primary total hip arthroplasty could have been avoided.</p></abstract><trans-abstract xml:lang="ru"><p><bold><italic>Актуальность.</italic></bold> Гетеротопическая оссификация (ГО) — это формирование зрелой кости в мягких тканях. ГО в области тазобедренного сустава может быть следствием как повреждения нервной системы, так и локальной травмы. После тотального эндопротезирования тазобедренного сустава ГО развивается в 30% наблюдений.</p> <p><bold><italic>Целью</italic></bold> публикации является демонстрация редкого клинического наблюдения пациента с рецидивом ГО после сложного первичного эндопротезирования тазобедренного сустава, сопровождающимся анкилозированием.</p> <p><bold><italic>Описание случая.</italic></bold> Пациент 32 лет поступил в клинику для ревизионного эндопротезирования тазобедренного сустава с диагнозом «застарелый вывих головки эндопротеза правого тазобедренного сустава, гетеротопическая оссификация» спустя 3 года после вывиха. Во время операции были сложности с выделением седалищного нерва, а также структур эндопротеза. Нами были удалены все оссификаты, которые препятствовали вывиху эндопротеза. У пациента наблюдалась невропатия седалищного нерва справа с поражением малоберцового и большеберцового нервов на фоне отека. Пациент был выписан на 21-й день. Представленный клинический случай интересен тем, что у пациента рецидив ГО мог быть обусловлен комбинацией различных факторов риска. С учетом того, что травма была получена в результате ДТП и у пациента имелся перелом костей контралатеральной голени, нельзя исключить эффект местной травмы тазобедренного сустава, усугубившей процесс.</p> <p><bold><italic>Заключение.</italic></bold> Данное клиническое наблюдение подчеркивает важность профилактики вероятных осложнений после операции и поддержания обратной связи с пациентами, особенно относящимися к группе высокого риска. Вполне вероятно, что при адекватной профилактике формирования ГО и своевременном вправлении вывиха описанных в статье проблем после первичного эндопротезирования удалось бы избежать.</p></trans-abstract><trans-abstract xml:lang="zh"><p/></trans-abstract><kwd-group xml:lang="en"><kwd>heterotopic ossification</kwd><kwd>hip arthroplasty</kwd><kwd>endoprosthesis dislocation</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>гетеротопическая оссификация</kwd><kwd>эндопротезирование</kwd><kwd>вывих эндопротеза</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Ranganathan K., Loder S., Agarwal S., Wong V.С., Forsberg J., Davis T.A. et al. Heterotopic Ossification: Basic-Science Principles and Clinical Correlates. J Bone Joint Surg Am. 2015;97(13):1101-1111. doi: 10.2106/JBJS.N.01056.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Yolcu Y.U., Wahood W., Goyal A., Alvi M.A., Reeves R.K., Qu W. et al. Factors Associated with Higher Rates of Heterotopic Ossification after Spinal Cord Injury: A Systematic Review and Meta-Analysis. Clin Neurol Neurosurg. 2020;195:105821. doi: 10.1016/j.clineuro.2020.105821.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Zhu Y., Zhang F., Chen W., Zhang Q., Liu S., Zhang Y. Incidence and risk factors for heterotopic ossification after total hip arthroplasty: a meta-analysis. Arch Orthop Trauma Surg. 2015;135(9):1307-1314. doi: 10.1007/s00402-015-2277-8.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Kan S.L., Yang B., Ning G.Z., Chen L.X., Li Y.L., Gao S.J., Chen X.C. et al. Nonsteroidal anti-inflammatory drugs as prophylaxis for heterotopic ossification after total hip arthroplasty. Medicine (Baltimore). 2015;94(18):e828. doi: 10.1097/MD.0000000000000828.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Kjaersgaard-Andersen P.K., Nafei A., Teichert G., Kristensen O., Schmidt S.A., Keller J. et al. Indomethacin for prevention of heterotopic ossification. A randomized controlled study in 41 hip arthroplasties. Acta Orthop Scand. 1993;64(6):639-642. doi: 10.3109/17453679308994587.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Mier P.D., van den Hurk J.J. Lysosomal hydrolases of the epidermis. I. Glycosidases. Br J Dermatol. 1975;93(1): 1-10. doi: 10.1111/j.1365-2133.1975.tb06468.x.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Brooker A.F., Bowerman J.W., Robinson R.A., Riley L.H. Jr. Ectopic ossification following total hip replacement. Incidence and a method of classification. J Bone Joint Surg Am. 1973;55(8):1629-1632.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Shehab D., Elgazzar A.H., Collier D.B. Heterotopic ossification. J Nucl Med. 2002;43(3):346-353.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Sullivan M.P., Torres S.J., Mehta S., Ahn J. Heterotopic ossification after central nervous system trauma: a current review. Bone Joint Res. 2013;2(3):51-57. doi: 10.1302/2046-3758.23.2000152.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Łęgosz P., Otworowski M., Sibilska A., Starszak K., Kotrych D., Kwapisz A. et al. Heterotopic Ossification: A Challenging Complication of Total Hip Arthroplasty: Risk Factors, Diagnosis, Prophylaxis, and Treatment. Biomed Res Int. 2019;2019:3860142. doi: 10.1155/2019/3860142.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Popovic M., Agarwal A., Zhang L., Yip C., Kreder H.J., Nousiainen M.T. et al. Radiotherapy for the prophylaxis of heterotopic ossification: a systematic review and meta-analysis of published data. Radiother Oncol. 2014;113:10-17. doi: 10.1016/j.radonc.2014.08.025.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Cholok D., Chung M.T., Ranganathan K., Ucer S., Day D., Davis T.A. et al. Heterotopic ossification and the elucidation of pathologic differentiation. Bone. 2018;109:12-21. doi: 10.1016/j.bone.2017.09.019.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Svircev J.N., Wallbom A.S. False-negative triple-phase bone scans in spinal cord injury to detect clinically suspect heterotopic ossification: a case series. J Spinal Cord Med. 2008;31:194-196. doi: 10.1080/10790268.2008.11760711.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Егиазарян К.А., Коробушкин Г.В., Сиротин И.В., Абилемец А.С., Юусибов Р.Р., Субботин Н.А. Клинический случай оперативного лечения приобретенной гетеротопической оссификации у пациента с тяжелой сочетанной травмой. Политравма. 2018;(2):75-81. Egiazaryan K.A., Korobushkin G.V., Sirotin I.V., Abilemets A.S., Yuusibov R.R., Subbotin N.A. [A clinical case of surgical treatment of acquired heterotopic ossification in a patient with polytrauma]. Polytravma [Polytrauma]. 2018; (2): 75-81. (In Russian).</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Молодов М.А., Даниляк В.В., Ключевский В.В., Гильфанов С.И., Ключевский В.В., Вергай А.А. Факторы риска вывихов тотальных эндопротезов тазобедренного сустава. Травматология и ортопедия России. 2013;(2):23-30. doi: 10.21823/2311-2905-2013-0-2-65-71. Molodov M.A., Danilyak V.V., Kluchevsky V.V., Gilfanov S.I., Kluchevsky V.V., Vergay A.A. [Risk factors for total hip arthroplasty dislocations]. Travmatologiya i ortopediya Rossii [Traumatology and Orthopedics of Russia]. 2013;19(2):23-30. (In Russian). doi: 10.21823/2311-2905-2013-0-2-65-71.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Vanden Bossche L.C., Van Maele G., Wojtowicz I., Bru I., Decorte T., De Muynck M. et al. Free radical scavengers versus methylprednisolone in the prevention of experimentally induced heterotopic ossification. J Orthop Res. 2009;27(6):748-751. doi: 10.1002/jor.20817.</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Romanò C.L., Duci D., Romanò D., Mazza M., Meani E. Celecoxib versus indomethacin in the prevention of heterotopic ossification after total hip arthroplasty. J Arthroplasty. 2004;19(1):14-18. doi: 10.1016/s0883-5403(03)00279-1.</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Jo S., J.H. Jimenez Almonte J.H., Sierra R.J. The Cumulative Risk of Re-dislocation After Revision THA Performed for Instability Increases Close to 35% at 15 years. J Arthroplasty. 2015;30(7):1177-1182. doi: 10.1016/j.arth.2015.02.001.</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Chalmers B.P., Ledford C.K., Taunton M.J., Sierra R.J., Lewallen D.G., Trousdale R.T. Cementation of a Dual Mobility Construct in Recurrently Dislocating and High Risk Patients Undergoing Revision Total Arthroplasty. J Arthroplasty. 2018;33(5):1501-1506. doi: 10.1016/j.arth.2017.11.055.</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Загородний Н.В., Бухтин К.М., Чрагян Г.А., Каграманов С.В., Галаев Х.И. Метод ревизии вертлужного компонента эндопротеза тазобедренного сустава без удаления ранее установленной чашки. Вестник травматологии и ортопедии им. Н.Н. Приорова. 2014;(4):73-74. doi: 10.17816/vto20140473-74. Zagorodniy N.V., Bukhtin K.M., Chragyan G.A., Kagramanov S.V., Galaev Kh.I. [Revision of hip endoprosthesis acetabular component without removal of reviously implanted cup]. Vestnik travmatologii i ortopedii im. N.N. Priorova [N.N. Priorov Journal of Traumatology and Orthopedics]. 2014;(4):73-74. (In Russian). doi: 10.17816/vto20140473-74.</mixed-citation></ref></ref-list></back></article>
