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Purpose of the study: to evaluate osteogenic rate of various characteristics of mechanical loading based on the authors’ data as well as literature analysis.

Literature analysis proved that clinical outcome of physical training can be achieved not only by increasing the mechanical load but also by altering number of load iterations, rate of load acceleration, frequency of cyclic load, rest interval, distribution of load across the skeleton. Presented data provides a reasonable basis to apply alterations of all above-mentioned load characteristics to obtain clinical effect and customize every single baseline exercise plan to gain a maximum treatment and preventive effect in individuals with high risk of osteoporotic fractures.

About the authors

A. S. Avrunin

Vreden Russian Research Institute of Traumatology and Orthopedics, ul. Ak. Baykova, 8, St. Petersburg, Russia, 195427

Author for correspondence.

senior researcher, the scientific department of the diagnosis and treatment of musculoskeletal system diseases and injuries, Vreden Russian Research Institute of Traumatology and Orthopedics

Russian Federation

A. A. Doktorov

All-Russian Research Institute on Medicinal and Aromatic Plants, ul. Grina, 7, str. 1, Moscow, Russia, 117216


professor, the head of morphology department, All-Russian Research Institute on Medicinal and Aromatic Plant

Russian Federation


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